Description

2-Fluoro-6-Methylpyridine-3-Trifluoroborate Potassium Salt is a high-value organotrifluoroborate reagent, a stable and versatile building block for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process R&D teams developing novel active ingredients, particularly in the pharmaceutical and crop protection industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, especially those containing fluorinated pyridine motifs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating novel fluorinated organic materials, such as ligands for catalysis or components for electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed carbon-carbon bond formation.
• Parallel and Combinatorial Chemistry: Ideal for high-throughput synthesis due to its stability, facilitating the rapid generation of compound libraries for screening.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and manufacturing scales for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Fluoro-6-Methylpyridine-3-Trifluoroborate Potassium Salt
CAS No.	1098173-30-8
Molecular Formula	C7H7BF4KN
Molecular Weight	231.04 g/mol
Synonyms	Potassium (2-Fluoro-6-methylpyridin-3-yl)trifluoroborate; 2-Fluoro-6-methyl-3-pyridinyltrifluoroborate Potassium Salt; 3-Trifluoroborato-2-fluoro-6-methylpyridine Potassium Salt; 2-Fluoro-6-methylpyridine-3-boronic acid trifluoroborate potassium salt; 2-Fluoro-6-methyl-3-pyridyltrifluoroboronate Potassium; Potassium 2-Fluoro-6-methylpyridine-3-trifluoroboronate; 2-Fluoro-6-methyl-3-pyridineboronic acid, trifluoroborate potassium complex
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methylpyridine-3-Trifluoroborate Potassium Salt is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (1H, 19F, 11B)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.