Description

(S)-(+)-2,2'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-6,6'-Dimethoxy-1,1'-Biphenyl,Min.97% is a high-purity, chiral bisphosphine ligand essential for asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, critical for producing single-isomer intermediates in fine chemical and pharmaceutical synthesis. This product is specifically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Used in the catalytic production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS, cardiovascular, and metabolic diseases.
• Agrochemical Manufacturing: Facilitates the synthesis of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Asymmetric C-C Bond Formation: Employed in cross-coupling and addition reactions to construct complex, stereodefined molecular architectures.
• Process Chemistry & Scale-up: Provides robust and reproducible performance for transitioning asymmetric catalytic processes from laboratory to pilot and commercial scale.
• Academic & Industrial R&D: Serves as a critical tool for developing new catalytic methodologies and exploring novel chemical space in discovery chemistry.

Basic Information

Item	Details
Product Name	(S)-(+)-2,2'-Bis[Di(3,5-Di-T-Butyl-4-Methoxyphenyl)Phosphino]-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97%
CAS No.	910134-30-4
Molecular Formula	C72H96O6P2
Molecular Weight	1119.48 g/mol
Synonyms	(S)-DTBM-SEGPHOS; (S)-5,5'-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-4,4'-bi-1,3-benzodioxole; (S)-DTBM-Segphos; (S)-3,3'-Di-tert-butyl-5,5',6,6'-tetramethoxy-2,2'-bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-1,1'-biphenyl; (S)-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-6,6'-dimethoxy-1,1'-biphenyl; SEGPHOS-DTBM; (S)-(+)-DTBM-SEGPHOS; (S)-DTBM-SegPhos ligand
EINECS	Contact for details

Quality Control

Our (S)-(+)-DTBM-SEGPHOS is manufactured under strict quality systems to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including chiral HPLC and 31P NMR, to confirm identity, enantiomeric purity, and a minimum assay of 97%. Certificates of Analysis (COA) with full analytical data are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to reference spectrum
Identification (31P NMR)	Conforms to reference spectrum
Assay (HPLC)	Min. 97.0%
Enantiomeric Purity (Chiral HPLC)	Min. 99.0% ee
Solubility	Soluble in common organic solvents (Toluene, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.