Description

Lithium 5-Bromo-Pyridine-2-Carboxylate is a high-purity organolithium reagent and a key synthetic intermediate in modern organic chemistry. This compound is valued for its role in facilitating challenging coupling reactions and constructing complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides that require bromo-substituted pyridine motifs.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Cross-Coupling Reactions: Acts as an organometallic reagent in palladium-catalyzed cross-coupling reactions, such as Negishi or Kumada couplings, to form new carbon-carbon bonds.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Material Science: A potential monomer or precursor for the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	Lithium 5-Bromo-Pyridine-2-Carboxylate
CAS No.	909711-99-5
Molecular Formula	C6H3BrLiNO2
Molecular Weight	199.95 g/mol
Synonyms	5-Bromopicolinic Acid Lithium Salt; Lithium 5-Bromopicolinate; 5-Bromo-2-pyridinecarboxylic Acid Lithium Salt; 5-Bromopyridine-2-carboxylic Acid Lithium Salt; 2-Pyridinecarboxylic Acid, 5-Bromo-, Lithium Salt; Lithium 5-Bromo-2-pyridinecarboxylate; Picolinic Acid, 5-Bromo-, Lithium Salt
EINECS	Contact for details

Quality Control

Our Lithium 5-Bromo-Pyridine-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect reactivity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.