Description

Lithium Phenoxide, 98 CAS NO 17634-93-4 is a versatile organolithium reagent and a powerful base, widely used in organic synthesis and industrial processes. Its high reactivity and selectivity make it a critical intermediate for constructing complex molecular architectures. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-purity materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating aryl ethers and facilitating deprotonation reactions.
• Polymerization Catalyst/Initiator: Used in the production of specialized polymers and resins, including certain types of phenolic resins and engineering plastics.
• Organic Synthesis Reagent: Acts as a strong, non-nucleophilic base for deprotonation and as a nucleophile in substitution reactions to form carbon-oxygen bonds.
• Agrochemical Synthesis: Intermediate in the manufacture of herbicides, fungicides, and other crop protection agents.
• Lithiation Agent: Employed for directed ortho-metalation (DoM) reactions to functionalize aromatic compounds regioselectively.
• Cross-Coupling Reactions: Serves as a precursor or transmetalation agent in palladium-catalyzed cross-coupling processes like the Suzuki-Miyaura reaction.

Basic Information

Product Name	Lithium Phenoxide, 98
CAS No.	17634-93-4
Molecular Formula	C6H5LiO
Molecular Weight	100.04 g/mol
Synonyms	Phenol, lithium salt; Lithium phenolate; Phenol lithium salt; Phenoxy lithium; Lithium carbolate; Lithiophenoxide; Phenyllithium oxide (obsolete); Lithium phenylate
EINECS	241-623-5

Quality Control

Our Lithium Phenoxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, assay, and impurity profiles. Certificates of Analysis (COA) documenting these results are available for every shipment. We adhere to relevant industry standards and can support requirements for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (Lithium Phenoxide)	≥ 98.0 %
Moisture (Karl Fischer)	≤ 1.0 %
Lithium Hydroxide (LiOH)	≤ 0.5 %
Phenol	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.