Description

Lithium Triisopropyl 2-(5-Fluoropyridyl)Borate is a specialized organoboron compound, specifically a lithium borate salt, with the CAS registry number 1048030-49-4. This chemical is a valuable reagent in modern synthetic chemistry, prized for its role as a sterically hindered, nucleophilic borate source. It is primarily utilized by research and development teams in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures, particularly in cross-coupling reactions and as a precursor for other boron-containing intermediates.

Application

• As a key reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds.
• As a nucleophilic borate source in the preparation of organoboronates and boronic esters.
• In the research and development of active pharmaceutical ingredients (APIs) and drug candidates.
• For the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• As a precursor or intermediate in the manufacture of specialty fine chemicals and ligands for catalysis.
• In academic and industrial R&D laboratories for methodological development in organometallic chemistry.

Basic Information

Item	Details
Product Name	Lithium Triisopropyl 2-(5-Fluoropyridyl)Borate
CAS No.	1048030-49-4
Molecular Formula	C14H24BF1LiN1
Molecular Weight	243.11 g/mol (Contact for details)
Synonyms	Lithium 2-(5-Fluoropyridin-2-yl)triisopropylborate; 2-(5-Fluoropyridin-2-yl)-1,3,2-dioxaborolane lithium salt (derivative); Triisopropyl(5-fluoro-2-pyridyl)borate lithium; Lithium (5-fluoro-2-pyridyl)triisopropylborate; LTB(5-FPy); (5-Fluoro-2-pyridyl)triisopropylboron lithium complex; Borate(1-), [2-(5-fluoropyridinyl)]triisopropyl-, lithium; Lithium triisopropyl(5-fluoro-2-pyridinyl)borate
EINECS	Contact for details

Quality Control

Our production of Lithium Triisopropyl 2-(5-Fluoropyridyl)Borate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analysis, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F) for structural confirmation and HPLC for purity assessment. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures must be avoided to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹H NMR Purity	≥ 97%
Water Content (KF)	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.