Description

Lithium, (4,5-Dimethyl-2-Thiazolyl)- (9Ci) is a specialized organolithium reagent featuring a functionalized thiazole moiety. This compound is valued for its role as a key synthetic intermediate, enabling precise carbon-lithium bond formation in complex organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of heterocyclic compounds with potential therapeutic activity.
• Agrochemical Research: Used in the creation of novel pesticides, herbicides, and fungicides that incorporate the thiazole ring system for enhanced biological activity.
• Ligand Precursor in Catalysis: Serves as a starting material for the preparation of specialized N-heterocyclic ligands used in transition metal catalysis.
• Material Science: Employed in the synthesis of organic electronic materials and functional polymers where the thiazole unit can influence electronic properties.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and contract research organization (CRO) laboratories.

Basic Information

Product Name	Lithium, (4,5-Dimethyl-2-Thiazolyl)- (9Ci)
CAS No.	122823-24-9
Molecular Formula	C5H6LiNS
Molecular Weight	119.11 g/mol
Synonyms	4,5-Dimethyl-2-thiazolyllithium; 2-Lithio-4,5-dimethylthiazole; (4,5-Dimethyl-1,3-thiazol-2-yl)lithium; Lithium (4,5-dimethyl-2-thiazolyl); 2-Thiazolyllithium, 4,5-dimethyl-; Lithium 4,5-dimethylthiazol-2-ide
EINECS	Contact for details

Quality Control

Our production of Lithium, (4,5-Dimethyl-2-Thiazolyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles, typically determined by NMR, HPLC, and titration methods. We support cGMP and ISO 9001 compliant manufacturing practices upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Due to its hygroscopic and pyrophoric nature, this reagent must be handled and stored under strictly anhydrous conditions. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to beige powder or solution
Identification (NMR)	Conforms to structure
Assay (Titration)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.