Description

4''-Propyl-3-Fluorobiphenyl-4-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and liquid crystal industries seeking to synthesize complex biphenyl-based target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biphenyl scaffolds.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the specific substitution pattern enhances biological activity and stability.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as those used in OLEDs and semiconductors.
• Liquid Crystal Compounds: Integral in the production of advanced liquid crystal mixtures for display technologies, where the propyl and fluorine groups fine-tune physical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and sensors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for CROs and CDMOs specializing in bespoke organic molecule production for client projects.

Basic Information

Product Name	4''-Propyl-3-Fluorobiphenyl-4-Boronic Acid
CAS No.	909709-42-8
Molecular Formula	C15H16BFO2
Molecular Weight	258.10 g/mol
Synonyms	4-(3-Fluoro-4'-propyl-[1,1'-biphenyl]-4-yl)boronic acid; 3-Fluoro-4'-propylbiphenyl-4-boronic acid; (3-Fluoro-4'-propyl-[1,1'-biphenyl]-4-yl)boronic acid; 4-Borono-3-fluoro-4'-propyl-1,1'-biphenyl; 909709-42-8; 4'-Propyl-3-fluorobiphenyl-4-ylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4''-Propyl-3-Fluorobiphenyl-4-Boronic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as assay purity (typically by HPLC/NMR) and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.