Description

(R)-2,2''-[5-Nitroisophthalamidobis(2,6-Pyridylenecarbamoylmethoxy)]-1,1''-Binaphthyl is a sophisticated chiral organic compound featuring a binaphthyl core integrated with pyridine and nitroisophthalamide functionalities. This complex molecular architecture makes it a highly valuable advanced intermediate or chiral ligand for asymmetric synthesis and catalysis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and high-performance materials.

Application

• Asymmetric Catalysis: Serves as a chiral ligand or catalyst precursor in transition metal-catalyzed reactions, such as hydrogenation, cross-coupling, and C-H activation.
• Pharmaceutical Intermediate: A key building block in the synthesis of complex, enantiomerically pure drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the research and development of novel, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Acts as a monomer or functional unit for constructing chiral polymers, supramolecular assemblies, and advanced organic frameworks (MOFs/COFs).
• Analytical Chiral Stationary Phases: Can be immobilized on silica to create high-performance liquid chromatography (HPLC) columns for enantiomer separation.
• Academic & Industrial R&D: A critical tool for chemists exploring new methodologies in stereoselective synthesis and molecular recognition.

Basic Information

Item	Detail
Product Name	(R)-2,2''-[5-Nitroisophthalamidobis(2,6-Pyridylenecarbamoylmethoxy)]-1,1''-Binaphthyl
CAS No.	909254-56-4
Molecular Formula	C54H36N8O10
Molecular Weight	956.92 g/mol
Synonyms	(R)-5-Nitro-N,N'-bis[6-({[(1,1'-binaphthalen)-2-yl]oxy}carbonyl)pyridin-2-yl]isophthalamide; (R)-Binaphthyl-based bis(pyridylamide) ligand; (R)-BINOL-pyridine hybrid ligand; (R)-2,2'-[5-Nitroisophthalamidobis(2,6-pyridinedicarboxamido)]-1,1'-binaphthyl; Chiral C2-symmetric amide ligand; CAS 909254-56-4
EINECS	Contact for details

Quality Control

Every batch of (R)-2,2''-[5-Nitroisophthalamidobis(2,6-Pyridylenecarbamoylmethoxy)]-1,1''-Binaphthyl is produced and tested under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.