Description

1-Bromo-2-Chloro-4-Ethoxy-3-Fluorobenzene is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. Its unique halogen and ether pattern makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine and halogen substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromatic core and functional handles.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aryl groups into target molecules.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where halogen and alkoxy groups modify color properties and lightfastness.
• Polymer Modifier: Acts as a monomer or functionalization agent for engineering plastics and high-performance polymers to impart specific chemical resistance or thermal properties.

Basic Information

Product Name	1-Bromo-2-Chloro-4-Ethoxy-3-Fluorobenzene
CAS No.	909122-17-4
Molecular Formula	C8H7BrClFO
Molecular Weight	253.50 g/mol
Synonyms	2-Bromo-1-Chloro-4-Ethoxy-3-Fluorobenzene; 3-Fluoro-4-ethoxy-1-bromo-2-chlorobenzene; 4-Ethoxy-3-fluoro-1-bromo-2-chlorobenzene; 1-Bromo-2-chloro-4-ethoxy-3-fluorobenzene; Benzene, 1-bromo-2-chloro-4-ethoxy-3-fluoro-; BCEFB (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4-Ethoxy-3-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.