Description

1-Chloro-3-Ethoxy-2-Fluorobenzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring halogen and alkoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic cores in electronic and optoelectronic materials.
• Organic Synthesis & Catalysis Research: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for studying new fluorination methodologies.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	1-Chloro-3-Ethoxy-2-Fluorobenzene
CAS No.	909122-16-3
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	2-Fluoro-3-chloro-1-ethoxybenzene; 3-Chloro-2-fluoro-1-ethoxybenzene; 1-Ethoxy-2-fluoro-3-chlorobenzene; Benzene, 1-chloro-3-ethoxy-2-fluoro-; 2-Fluoro-3-chlorophenetole
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Ethoxy-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.