Description

1-Bromo-3-Chloro-4-Ethoxy-2-Fluorobenzene is a high-purity, multi-substituted benzene derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen and ether substitution pattern makes it an invaluable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides due to its halogenated aromatic structure.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex aromatic fragments.
• Laboratory Reagent: Used in academic and industrial R&D settings for method development and exploratory synthesis.

Basic Information

Product Name	1-Bromo-3-Chloro-4-Ethoxy-2-Fluorobenzene
CAS No.	909122-14-1
Molecular Formula	C8H7BrClFO
Molecular Weight	253.50 g/mol
Synonyms	2-Fluoro-4-ethoxy-1-bromo-3-chlorobenzene; 4-Ethoxy-2-fluoro-1-bromo-3-chlorobenzene; 3-Chloro-4-ethoxy-2-fluorobromobenzene; Benzene, 1-bromo-3-chloro-4-ethoxy-2-fluoro-; 909122-14-1
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-4-Ethoxy-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.