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Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-Amide CAS NO 908844-75-7
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CAS No.:908844-75-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-Amide is a synthetic peptide fragment derived from the neuropeptide galanin, designed for high-purity research and development applications. This compound is critical for advanced studies in neurobiology, endocrinology, and peptide-based drug discovery due to its specific receptor interaction profile. It serves as an essential tool for pharmaceutical R&D teams, academic researchers, and biotechnology companies investigating neurological pathways, metabolic regulation, and novel therapeutic agents.
Application
- Neuroscientific Research: Used as a selective ligand and reference standard in receptor binding assays and signal transduction studies to elucidate the role of galanin in the central and peripheral nervous systems.
- Drug Discovery & Development: Serves as a key intermediate or pharmacophore model for designing and screening novel peptide-based therapeutics targeting galanin receptors for conditions like pain, epilepsy, and metabolic disorders.
- Biochemical Assay Development: Employed as a calibration standard in analytical method development (e.g., HPLC, LC-MS) for quantifying galanin-related peptides in complex biological matrices.
- Academic & Institutional Research: Provides a high-purity reagent for fundamental research into peptide structure-activity relationships (SAR) and neuropeptide function.
- In Vitro Diagnostics (IVD): May be utilized in the development of specialized immunoassays and diagnostic kits for research purposes.
Basic Information
| Product Name | Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-Amide |
| CAS No. | 908844-75-7 |
| Molecular Formula | C84H130N26O23 |
| Molecular Weight | 1799.1 g/mol |
| Synonyms | Galanin (2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-NH2; Galanin Fragment (2-13); [Glu1,His2,3xPro]Galanin(2-13); Galanin-Related Peptide; Synthetic Galanin Analog; GAL(2-13) analog; Neuropeptide Galanin Fragment |
| EINECS | Contact for details |
Quality Control
Every batch of Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-Amide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol is designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), peptide content, and impurity profiles is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% (by weight) |
| Single Impurity (HPLC) | ≤ 1.0% |
| Amino Acid Analysis | Within ± 10% of theoretical |
| Water Content (KF) | ≤ 5.0% |
| Acetate Content (HPLC) | ≤ 10.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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