Description

(S)-Thiazolidine-4-Carbonitrile is a chiral, non-natural amino acid derivative featuring a thiazolidine ring system. This compound serves as a versatile and high-value building block in modern organic synthesis, particularly for the construction of complex molecules with defined stereochemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Peptidomimetics Research: Used to introduce constrained, sulfur-containing heterocycles into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Agrochemical Synthesis: Employed in the R&D of advanced herbicides and fungicides with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Material Science: Investigated as a monomer or precursor for specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	(S)-Thiazolidine-4-Carbonitrile
CAS No.	908290-83-5
Molecular Formula	C4H6N2S
Molecular Weight	114.17 g/mol
Synonyms	(4S)-Thiazolidine-4-carbonitrile; (S)-4-Cyanothiazolidine; L-Thiazolidine-4-carbonitrile; (S)-(-)-Thiazolidine-4-carbonitrile; 4-Thiazolidinecarbonitrile, (4S)-; 908290-83-5; (S)-Thiazolidinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of (S)-Thiazolidine-4-Carbonitrile is produced and tested under strict quality management protocols. We guarantee high chiral purity and chemical consistency to meet the exacting standards of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.