Description

3-Fluoro-1-Iodo-2,4-Dimethoxybenzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring fluorine and iodine substituents on a dimethoxybenzene scaffold, makes it a versatile precursor for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorine and iodine atoms into complex molecular architectures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the halogenated aromatic core can contribute to biological activity.
• Material Science Precursor: Acts as a building block for organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings for carbon-carbon bond formation.
• Fluorine Chemistry Studies: Utilized in research focused on the effects of fluorine substitution on the physical, chemical, and biological properties of organic compounds.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis.

Basic Information

Item	Details
Product Name	3-Fluoro-1-Iodo-2,4-Dimethoxybenzene
CAS No.	905752-13-8
Molecular Formula	C8H8FIO2
Molecular Weight	282.05 g/mol
Synonyms	1-Iodo-3-fluoro-2,4-dimethoxybenzene; 2,4-Dimethoxy-3-fluoroiodobenzene; 3-Fluoro-2,4-dimethoxy-1-iodobenzene; 905752-13-8; Benzene, 3-fluoro-1-iodo-2,4-dimethoxy-; 3-Fluoro-2,4-dimethoxyiodobenzene; 3-Fluoro-1-iodo-2,4-dimethoxy-benzene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-1-Iodo-2,4-Dimethoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.