Description

3,4-Difluoro-2-Methoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through pivotal cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific difluoromethoxy-substituted aromatic cores.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification and validation.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	3,4-Difluoro-2-Methoxyphenylboronic Acid
CAS No.	905583-06-4
Molecular Formula	C7H7BF2O3
Molecular Weight	187.94 g/mol
Synonyms	(3,4-Difluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-3,4-difluorophenylboronic acid; 3,4-Difluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(3,4-difluoro-2-methoxyphenyl)-; 905583-06-4; 3,4-Difluoro-o-anisylboronic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.