Description

2-Pyrrolidinecarboxamide, 3-Hydroxy-N,n-Dimethyl-, (2S,3S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique pyrrolidine scaffold and functional groups, which make it a versatile intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in neurological and metabolic disorder therapies.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Peptidomimetics Development: The pyrrolidine core is valuable for creating conformationally restricted peptide analogs.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	2-Pyrrolidinecarboxamide, 3-Hydroxy-N,n-Dimethyl-, (2S,3S)-
CAS No.	905079-54-1
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(2S,3S)-3-Hydroxy-N,N-dimethylpyrrolidine-2-carboxamide; (2S,3S)-3-Hydroxy-1-methyl-2-pyrrolidinecarboxamide; (2S,3S)-N,N-Dimethyl-3-hydroxypyrrolidine-2-carboxamide; L-threo-3-Hydroxy-N,N-dimethylpyrrolidine-2-carboxamide; (2S,3S)-3-Hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide; A chiral hydroxy pyrrolidine carboxamide derivative.
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxamide, 3-Hydroxy-N,n-Dimethyl-, (2S,3S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2S,3S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.