Description

Uridine 5'-Diphospho-α-D-Glucose-13C6 Diammonium Salt is a stable, isotopically labeled ammonium salt form of UDP-glucose, where the glucose moiety is uniformly labeled with carbon-13. This compound is a critical biochemical reagent, providing a stable, high-purity standard for quantitative metabolic flux analysis and research into glycosylation pathways. It is essential for scientists and manufacturers in pharmaceutical research, metabolic engineering, and advanced biochemical diagnostics who require precise, traceable standards for mass spectrometry and NMR studies.

Application

• Metabolic Flux Analysis (MFA): Serves as a key labeled precursor for tracing glucose metabolism and nucleotide sugar pathways in cell cultures and biological systems using LC-MS or GC-MS.
• Glycobiology Research: Used as a substrate for glycosyltransferases to study enzymatic activity, specificity, and the biosynthesis of glycoproteins, glycolipids, and proteoglycans.
• Pharmaceutical Development: Acts as an internal standard for the quantitative analysis of UDP-sugars in drug metabolism and pharmacokinetics (DMPK) studies.
• Biochemical Assay Standard: Provides a certified reference material for calibrating instruments and validating analytical methods in quality control laboratories.
• Enzyme Kinetics Studies: Employed to investigate the kinetics and mechanisms of enzymes involved in sugar nucleotide metabolism.
• Diagnostic Kit Manufacturing: Incorporated as a critical component in high-sensitivity diagnostic kits for inborn errors of metabolism related to glycosylation.

Basic Information

Product Name	Uridine 5'-Diphospho-α-D-Glucose-13C6 Diammonium Salt
CAS No.	904293-00-1
Molecular Formula	C1513C6H30N4O17P2 • 2(NH4)
Molecular Weight	Contact for details
Synonyms	UDP-α-D-Glucose-13C6 Diammonium Salt; UDP-Glc-13C6 Diammonium Salt; Uridine diphosphate glucose-13C6 diammonium salt; UDP-D-Glucose-13C6 Diammonium Salt; Uridine 5'-(α-D-glucopyranosyl diphosphate)-13C6 diammonium salt; 1-[(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-13C6-oxan-2-yl] 3-[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl] hydrogen diphosphate diammonium salt
EINECS	Contact for details

Quality Control

Our Uridine 5'-Diphospho-α-D-Glucose-13C6 Diammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and impurities are provided to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Isotopic Enrichment (MS)	≥ 99 atom % 13C (in glucose moiety)
Water Content (KF)	≤ 5.0 %
Ammonium Content	Conforms to theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.