Description

Acetyl-Amyloid β-Protein (1-6) is a chemically modified peptide fragment derived from the N-terminal region of the amyloid-β protein. This acetylated derivative is of significant value in biochemical and neurological research, particularly for studying protein aggregation mechanisms and developing diagnostic tools. It is primarily utilized by researchers and pharmaceutical developers in the fields of neuroscience, Alzheimer's disease research, and peptide-based therapeutic discovery.

Application

• Biochemical Research: Used as a reference standard or substrate in studies investigating the aggregation kinetics and toxicity of amyloid-β peptides.
• Neuroscience Studies: Applied in in vitro and cellular models to understand the molecular pathogenesis of Alzheimer's disease and related dementias.
• Diagnostic Development: Serves as a key antigen or component in the development of immunoassays and biosensors for detecting amyloid-β species.
• Drug Discovery Screening: Employed in high-throughput screening assays to identify and evaluate potential inhibitors of amyloid-β aggregation.
• Peptide Chemistry: Acts as a building block or intermediate for the synthesis of longer, modified amyloid-β peptide sequences for specialized research applications.

Basic Information

Product Name	Acetyl-Amyloid β-Protein (1-6)
CAS No.	903883-22-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ac-Aβ(1-6); Acetyl-Amyloid Beta (1-6); N-Acetyl-Aβ1-6; Ac-Aβ1-6 peptide; Acetylated Amyloid-β Protein Fragment 1-6; Nα-Acetyl-Aβ(1-6); Ac-DAEFRH-OH
EINECS	Contact for details

Quality Control

Our Acetyl-Amyloid β-Protein (1-6) is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC and MS, to ensure high purity and correct sequence verification. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.