Description

Boronic Acid, [4-Chloro-3-(Trifluoromethoxy)Phenyl]- is a high-purity, synthetically valuable organoboron compound. This chemical serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions to form carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients. Its specific substitution pattern makes it a sought-after intermediate for creating complex molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Boronic Acid, [4-Chloro-3-(Trifluoromethoxy)Phenyl]-
CAS No.	902757-07-7
Molecular Formula	C7H5BClF3O3
Molecular Weight	239.38 g/mol
Synonyms	[4-Chloro-3-(trifluoromethoxy)phenyl]boronic acid; (4-Chloro-3-(trifluoromethoxy)phenyl)boronic acid; 4-Chloro-3-(trifluoromethoxy)benzeneboronic acid; B-[4-Chloro-3-(trifluoromethoxy)phenyl]boronic acid; 902757-07-7; 4-Chloro-α,α,α-trifluoro-3-methoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of Boronic Acid, [4-Chloro-3-(Trifluoromethoxy)Phenyl]- is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.