Description

(2,4-Difluoro-5-Methylphenyl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and specialty polymer development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a difluoromethylphenyl motif.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures for enhanced bioactivity and stability.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for palladium-catalyzed coupling with aryl/vinyl halides, enabling efficient biaryl and conjugated system construction.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated aromatic units tune electronic properties.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Utilized to create fluorinated molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	(2,4-Difluoro-5-Methylphenyl)Boronic Acid
CAS No.	900175-09-9
Molecular Formula	C7H7BF2O2
Molecular Weight	171.94 g/mol
Synonyms	2,4-Difluoro-5-methylbenzeneboronic acid; (5-Methyl-2,4-difluorophenyl)boronic acid; B-(2,4-Difluoro-5-methylphenyl)boronic acid; 2,4-Difluoro-5-methylphenylboronic acid; 900175-09-9; Boronic acid, B-(2,4-difluoro-5-methylphenyl)-; AKOS005258065
EINECS	Contact for details

Quality Control

Our (2,4-Difluoro-5-Methylphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when weighing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.