Description

5-Ethyl-2-Fluorophenylboronic Acid is a high-purity organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated biphenyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the ethyl-fluorophenyl moiety imparts specific biological activity and stability.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences industry.

Basic Information

Product Name	5-Ethyl-2-Fluorophenylboronic Acid
CAS No.	900175-03-3
Molecular Formula	C8H10BFO2
Molecular Weight	167.98 g/mol
Synonyms	(5-Ethyl-2-fluorophenyl)boronic acid; 2-Fluoro-5-ethylbenzeneboronic acid; 5-Ethyl-2-fluorobenzeneboronic acid; Boronic acid, B-(5-ethyl-2-fluorophenyl)-; 900175-03-3; (5-Ethyl-2-fluorophenyl)boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 5-Ethyl-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals (ICP-MS)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.