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5-Ethoxy-2-Fluorophenylboronic Acid CAS NO 900174-60-9


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CAS No.:900174-60-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Ethoxy-2-Fluorophenylboronic Acid is a high-purity organoboron compound, specifically a fluorinated arylboronic acid derivative. This chemical serves as a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds through cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in novel drug candidates.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorine and ethoxy substituents for bioactivity.
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
  • Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes and sensors.
  • Catalyst & Ligand Development: Serves as a starting material for creating novel palladium catalyst ligands or other organometallic complexes.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated boronic acids.

Basic Information

Product Name 5-Ethoxy-2-Fluorophenylboronic Acid
CAS No. 900174-60-9
Molecular Formula C8H10BFO3
Molecular Weight 183.98 g/mol
Synonyms (5-Ethoxy-2-fluorophenyl)boronic acid; 2-Fluoro-5-ethoxyphenylboronic acid; 5-Ethoxy-2-fluorobenzeneboronic acid; Boronic acid, B-(5-ethoxy-2-fluorophenyl)-; 900174-60-9; 5-Ethoxy-2-fluoro-benzeneboronic acid
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Quality Control

Our 5-Ethoxy-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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