Description

(S)-n-(2-(2-Formyl-1-Pyrrolidinyl)-2-Oxoethyl)Acetamide is a high-purity chiral intermediate featuring a formylpyrrolidine scaffold. This compound is valued for its role in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and metabolic pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and enzyme inhibitor therapies.
• Protease Inhibitor Research: Used in the development and study of protease inhibitors due to its structural similarity to peptide mimetics.
• Asymmetric Synthesis: Serves as a precursor or reagent in asymmetric catalytic reactions to introduce stereochemical complexity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Bioconjugation Chemistry: The reactive formyl group can be utilized for site-specific bioconjugation and labeling applications.
• Custom Synthesis: A starting material for the custom synthesis of specialized compounds for clinical research and development.

Basic Information

Product Name	(S)-n-(2-(2-Formyl-1-Pyrrolidinyl)-2-Oxoethyl)Acetamide
CAS No.	99952-49-5
Molecular Formula	C9H14N2O3
Molecular Weight	198.22 g/mol
Synonyms	(S)-N-(2-(2-Formyl-1-pyrrolidinyl)-2-oxoethyl)acetamide; (S)-2-Acetamido-N-(2-formylpyrrolidin-1-yl)-2-oxoacetamide; (S)-Acetamide, N-[2-(2-formyl-1-pyrrolidinyl)-2-oxoethyl]-; (S)-1-(2-Acetamido-2-oxoethyl)-2-formylpyrrolidine; (S)-2-Formyl-1-(2-oxo-2-(acetamido)ethyl)pyrrolidine; (S)-Glyoxylamide, N-acetyl-, (2-formylpyrrolidin-1-yl)-; Chiral Formylpyrrolidine Acetamide Derivative
EINECS	Contact for details

Quality Control

Our (S)-n-(2-(2-Formyl-1-Pyrrolidinyl)-2-Oxoethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.