Description

(D(Ch)1,D-Phe2,Ile,Ala-Nh)-Vasopressin CAS NO 99835-78-6 is a synthetic, non-natural analog of the neurohypophysial hormone vasopressin, designed for enhanced stability and specific receptor interaction. This compound is critical for advanced biochemical and pharmacological research, offering a valuable tool for studying vasopressin receptor subtypes and their signaling pathways. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroendocrinology, metabolic disorders, and peptide-based drug discovery.

Application

• Pharmacological Research: As a selective ligand for studying the structure-activity relationships (SAR) of vasopressin and oxytocin receptor families.
• Biochemical Assay Development: Used as a reference standard or active component in receptor binding assays and functional cellular tests.
• Drug Discovery Programs: Serves as a lead compound or molecular scaffold for developing novel therapeutics targeting conditions like diabetes insipidus, septic shock, or cognitive disorders.
• Neuroscience Studies: Investigation of the role of vasopressin analogs in social behavior, memory, and central autonomic regulation.
• Peptide Chemistry & Stability Studies: A model compound for researching the effects of D-amino acid and other non-natural substitutions on peptide stability, bioavailability, and metabolic resistance.

Basic Information

Product Name	(D(Ch)1,D-Phe2,Ile,Ala-Nh)-Vasopressin
CAS No.	99835-78-6
Molecular Formula	C52H74N14O12S2
Molecular Weight	1111.36 g/mol
Synonyms	d(CH2)5[D-Phe2,Ile4,Ala-NH29]AVP; Desmopressin analog; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid, 2-D-phenylalanine, 4-isoleucine, 9-alaninamide]vasopressin; AVP antagonist analog; Vasopressin V1a receptor ligand; (1-β-Mercaptocyclohexaneacetic acid)-2-D-Phe-4-Ile-8-Ala-NH2-vasopressin; [d(CH2)51,D-Phe2,Ile4,Ala-NH29]VP
EINECS	Contact for details

Quality Control

Every batch of our (D(Ch)1,D-Phe2,Ile,Ala-Nh)-Vasopressin is produced and analyzed under strict quality management systems. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive testing includes identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.