Description

4-Amino-3-Bromo-5-Methyl-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound matters for its role as a critical intermediate in the synthesis of complex organic molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogen and amino functional groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom chemical synthesis services targeting niche applications.
• Academic and Industrial R&D: Utilized in exploratory chemistry for constructing complex heterocyclic compounds and novel chemical entities.

Basic Information

Product Name	4-Amino-3-Bromo-5-Methyl-Benzonitrile
CAS No.	99799-46-9
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	3-Bromo-4-amino-5-methylbenzonitrile; 5-Methyl-3-bromo-4-aminobenzonitrile; 4-Amino-3-bromo-5-methylbenzonitrile; Benzonitrile, 4-amino-3-bromo-5-methyl-; 2-Bromo-6-cyano-4-methylaniline; 4-Methyl-6-bromo-2-cyanoaniline; 99799-46-9
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-5-Methyl-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Single Maximum Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.