Description

1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-6-[(Triphenylphosphoranylidene)Amino]-5-Pyrimidinecarboxylic Acid Ethyl Ester is a specialized heterocyclic compound featuring a unique ylide-substituted pyrimidine core. This structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily sought after by research institutions and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic APIs, particularly those with pyrimidine-based pharmacophores.
• Organic Synthesis Building Block: Utilized in the construction of complex molecules for medicinal chemistry research and process development.
• Wittig Reaction Reagent: The triphenylphosphoranylidene (ylide) moiety can act as a reagent for olefination reactions in specialized synthetic pathways.
• Agrochemical Research: Serves as an intermediate in the development of novel pesticides and herbicides with specific biological activity.
• Material Science Research: Potential building block for creating novel organic electronic materials or ligands for catalysis.
• Academic & Industrial R&D: Used in method development and exploratory chemistry for new reaction discovery.

Basic Information

Product Name	1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-6-[(Triphenylphosphoranylidene)Amino]-5-Pyrimidinecarboxylic Acid Ethyl Ester
CAS No.	99747-55-4
Molecular Formula	C27H26N3O4P
Molecular Weight	487.49 g/mol
Synonyms	6-[(Triphenylphosphoranylidene)amino]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylic acid ethyl ester; Ethyl 1,3-dimethyl-2,4-dioxo-6-(triphenyl-λ5-phosphanylideneamino)-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 6-(Triphenylphosphoranylideneamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic Acid Ethyl Ester; Ylide-Substituted Pyrimidine Ester; TPAP Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.