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1-Boc-1,7-Diaminoheptane CAS NO 99733-18-3


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CAS No.:99733-18-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Boc-1,7-Diaminoheptane is a high-purity, protected diamine building block of significant importance in advanced organic synthesis. Its primary value lies in its bifunctional nature, where the Boc (tert-butoxycarbonyl) group provides orthogonal protection for one amine, allowing for selective modification of the other. This compound is essential for researchers and manufacturers in the pharmaceutical and bioconjugation sectors, particularly for the synthesis of complex molecules, peptide mimetics, and specialized polymers.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a linear diamine spacer.
  • Peptide & Peptidomimetic Synthesis: Used to introduce a protected, elongated diamine chain into peptide backbones to modify structure, stability, and biological activity.
  • Bioconjugation & Linker Chemistry: Serves as a versatile linker for attaching drugs, dyes, or other functional groups to proteins, antibodies, or nanoparticles.
  • Polymer & Material Science: Employed as a monomer or cross-linking agent in the production of polyamides, polyurethanes, and other specialty polymers.
  • Chemical Research & Development: A valuable reagent in medicinal chemistry for constructing compound libraries and exploring structure-activity relationships (SAR).
  • Ligand & Catalyst Synthesis: Used to prepare chelating ligands for metal complexes in catalytic and sensing applications.

Basic Information

Product Name 1-Boc-1,7-Diaminoheptane
CAS No. 99733-18-3
Molecular Formula C₁₂H₂₆N₂O₂
Molecular Weight 230.35 g/mol
Synonyms N1-Boc-1,7-Heptanediamine; 1,7-Heptanediamine, N1-(1,1-dimethylethoxy)carbonyl]-; N-(tert-Butoxycarbonyl)-1,7-diaminoheptane; N-Boc-1,7-diaminoheptane; tert-Butyl (7-aminoheptyl)carbamate; Boc-DAH; Boc-1,7-diaminoheptane; 7-[(tert-Butoxycarbonyl)amino]heptan-1-amine
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Quality Control

Our 1-Boc-1,7-Diaminoheptane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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