Description

Propionic Acid, 2-Acetamido-2-Amino-3-Chloro- (6Ci) is a specialized chlorinated amino acid derivative with a propionic acid backbone. This compound serves as a crucial high-purity building block in advanced organic synthesis, enabling the development of complex molecular architectures. It is primarily utilized by pharmaceutical research and fine chemical industries for applications requiring precise chemical modification and chiral synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptidomimetic Research: Used to incorporate modified amino acid residues into peptide analogs to enhance stability and biological activity.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Employed in creating chiral ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation Chemistry: Useful for modifying biomolecules (proteins, antibodies) due to its reactive functional groups.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Item	Details
Product Name	Propionic Acid, 2-Acetamido-2-Amino-3-Chloro- (6Ci)
CAS No.	99586-44-4
Molecular Formula	C5H9ClN2O3
Molecular Weight	180.59 g/mol
Synonyms	2-Acetamido-2-amino-3-chloropropionic acid; 3-Chloro-2-amino-2-acetamidopropionic acid; 2-Amino-2-acetamido-3-chloropropanoic acid; (2R/S)-2-Acetamido-2-amino-3-chloropropionic acid; NSC 163044; Chlorinated D-amino acid derivative; Ac-Cl-Dap-OH derivative; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our Propionic Acid, 2-Acetamido-2-Amino-3-Chloro- (6Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.