Description

[1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,cis-(9Ci) CAS NO 99299-41-9 is a specialized bicyclopropyl amino acid derivative, a high-value chiral building block in advanced organic synthesis. Its unique constrained bicyclic structure and cis-configuration make it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where its rigid structure can impart favorable biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Peptidomimetics and Bioisosteres: Its conformationally restricted amino acid structure is valuable for designing peptide analogs and bioisosteres in drug discovery.
• Material Science Research: Investigated as a monomer or building block for novel polymers and functional materials with unique properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Item	Detail
Product Name	[1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,cis-(9Ci)
CAS No.	99299-41-9
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	cis-2-Amino[1,1'-bicyclopropane]-2-carboxylic acid; (1S,2S)-2-Aminobicyclo[1.1.0]butane-1-carboxylic acid; Bicyclopropyl amino acid; cis-BCP-AA; 2-Aminobicyclo[1.1.0]butane-1-carboxylic acid, cis-; 99299-41-9; Amino bicyclopropane carboxylic acid
EINECS	Contact for details

Quality Control

Our [1,1-Bicyclopropyl]-2-Carboxylicacid,2-Amino-,cis-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We support development from milligram to kilogram scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.