Description

Human Neutrophil Peptide-2 (HNP-2) is a cationic antimicrobial peptide, a key component of the innate immune system's defense against microbial pathogens. This peptide is crucial for research and development in immunology and infectious disease, offering insights into host defense mechanisms and potential therapeutic applications. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in antimicrobial, anti-inflammatory, and immunomodulatory studies.

Application

• Immunological Research: Fundamental studies on neutrophil function, innate immunity, and host-pathogen interactions.
• Antimicrobial Agent Development: Investigation as a template for novel antibiotic peptides targeting drug-resistant bacteria.
• Biomarker Studies: Analysis of HNP-2 levels in biological fluids as a potential biomarker for inflammatory and infectious diseases.
• Pharmaceutical R&D: Pre-clinical evaluation for therapeutic applications in sepsis, wound healing, and chronic infections.
• Cell Biology Assays: Used in vitro to study peptide-induced membrane permeabilization and cell signaling pathways.
• Diagnostic Reagent Component: Potential use in the development of immunoassays and diagnostic kits.

Basic Information

Product Name	Human Neutrophil Peptide-2
CAS No.	99287-07-7
Molecular Formula	C95H141N39O31S3
Molecular Weight	~ 2372.6 g/mol
Synonyms	HNP-2; Defensin, alpha 2; Neutrophil Defensin 2; Defensin Alpha 2, Human; HP-2; Human Neutrophil Peptide 2; DEFA2; HNP2; Antimicrobial Peptide HNP-2
EINECS	Contact for details

Quality Control

Our Human Neutrophil Peptide-2 is produced and tested under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to relevant guidelines for peptide synthesis and characterization to support your scientific integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.