Description

Hemoglobin Doha CAS NO 99241-60-8 is a specific variant of hemoglobin, a crucial oxygen-transporting metalloprotein found in red blood cells. This compound is of significant interest in biochemical research and diagnostic development due to its unique structural and functional properties. It serves as an essential reference standard and raw material for researchers and manufacturers in the life sciences, pharmaceutical, and in-vitro diagnostic (IVD) industries.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Reagents: A key component in the calibration and quality control of clinical analyzers and hemoglobinopathy testing kits.
• Pharmaceutical Development: Employed in research for blood substitutes and oxygen-carrier therapeutics.
• Hematology Standards: Serves as a critical material for manufacturing certified reference materials (CRMs) used in clinical laboratories.
• Educational & Training: Utilized in academic and professional settings for teaching advanced concepts in protein chemistry and hematology.

Basic Information

Product Name	Hemoglobin Doha
CAS No.	99241-60-8
Molecular Formula	C2952H4664N812O832S8Fe4
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Doha; Hemoglobin variant Doha; Unstable hemoglobin Doha; α-2 β-2(121(GH4)Glu->Lys); HBB:c.364G>A; Hemoglobin alpha chain; Hemoglobin beta chain; Oxyhemoglobin Doha
EINECS	Contact for details

Quality Control

Our Hemoglobin Doha is produced and handled under stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including purity assay, spectral analysis, and stability checks, to ensure it meets the exacting requirements of research and diagnostic applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (UV-Vis)	Complies (Soret band ~414 nm)
Purity (HPLC)	≥ 95% (Hemoglobin Doha)
Assay (Spectrophotometric)	≥ 90% of theoretical
Methemoglobin Content	< 5%
Solubility	Clear solution in buffer
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.