Description

Pantothenate Permease, E Coli is a specialized membrane protein complex that facilitates the active transport of pantothenate (vitamin B5) across the cell membrane of Escherichia coli. This compound is critical for research in microbial physiology, membrane transport mechanisms, and antibiotic development, as pantothenate is a vital precursor for coenzyme A biosynthesis. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway studies, target validation, and the discovery of novel antimicrobial agents.

Application

• Membrane Transport Research: Fundamental studies on the structure, function, and kinetics of secondary active transport systems in prokaryotes.
• Antimicrobial Target Validation: Serves as a potential target for developing novel antibiotics that disrupt essential vitamin uptake in pathogenic bacteria.
• Metabolic Engineering: Used in synthetic biology and metabolic pathway optimization in E. coli platforms for the production of vitamins, cofactors, or related compounds.
• Biochemical Assay Development: A key component in in vitro assays to screen for inhibitors or modulators of pantothenate uptake.
• Nutritional Microbiology: Research into bacterial growth requirements and the role of vitamin B5 in microbial ecosystems.
• Protein-Protein Interaction Studies: Investigation of the permease complex's interactions with other cellular components and regulatory factors.

Basic Information

Item	Details
Product Name	Pantothenate Permease, E Coli
CAS No.	99194-01-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PanF Permease; Vitamin B5 Transporter, E. coli; Pantothenate Transporter; PanF Protein; High-Affinity Pantothenate Permease; E. coli PanF; Pantothenic Acid Transport Protein
EINECS	Contact for details

Quality Control

Our Pantothenate Permease, E Coli is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized for purity and functionality. A comprehensive Certificate of Analysis (COA) detailing specific tests such as protein concentration, purity assessment (e.g., SDS-PAGE), and functional activity is provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Aliquot to avoid repeated freeze-thaw cycles. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Protein Concentration	As per COA
Purity (SDS-PAGE)	> 90%
Biological Activity	Assessed by transport assay
Buffer Composition	Specified on COA
Endotoxin Level	< 1.0 EU/µg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.