Description

1,3,5[10]-Estratriene-3,17Beta-Diol 3-Glucuronide 17-Sulfate Dipotassium Salt is a high-purity, conjugated metabolite of estradiol, specifically designed for research and development applications requiring well-characterized reference standards. This compound is critical for analytical method development, calibration, and quality control in bioanalytical studies. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and diagnostic manufacturers focused on endocrine and metabolic pathway analysis.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantification of estrogen metabolites in biological matrices via LC-MS/MS or HPLC.
• Clinical Research & Diagnostics: Used in the development and validation of diagnostic assays for hormone-related disorders and metabolic studies.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to investigate sulfotransferase and glucuronidase activities.
• Metabolite Identification: Essential for the structural confirmation and profiling of estrogen metabolism pathways in drug development.
• Quality Control: Acts as an internal standard for ensuring accuracy and precision in analytical laboratories.

Basic Information

Product Name	1,3,5[10]-Estratriene-3,17Beta-Diol 3-Glucuronide 17-Sulfate Dipotassium Salt
CAS No.	99156-45-3
Molecular Formula	C24H30K2O13S
Molecular Weight	660.75 g/mol
Synonyms	Estradiol-3-Glucuronide-17-Sulfate Dipotassium Salt; Estratriene-3,17β-diol 3-glucuronide 17-sulfate dipotassium; 17β-Estradiol 3-Glucuronide 17-Sulfate Dipotassium; K2-E2-3G-17S; Estrogen Metabolite Conjugate; E2-3G-17S Dipotassium Salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for reference materials. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) with detailed chromatographic data and batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Assay	90.0% - 110.0% of labeled amount

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.