Description

(αr,3S)-3-[[(R)-[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]Hydroxyacetyl]Amino]-3-(Formylamino)-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is a complex, high-purity azetidinone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of novel β-lactam antibiotics and other biologically active molecules. It is essential for research institutions and pharmaceutical companies focused on developing next-generation antimicrobial agents and exploring new therapeutic pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel β-lactam antibiotics.
• Antimicrobial Research: Used as a precursor in studies targeting new mechanisms of action against drug-resistant bacteria.
• Chemical Biology: Serves as a probe or building block in the study of enzyme inhibition and protein-ligand interactions.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis.
• Pre-clinical Development: Integral to the synthesis of candidate drug molecules for pharmacological and toxicological evaluation.

Basic Information

Product Name	(αr,3S)-3-[[(R)-[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]Hydroxyacetyl]Amino]-3-(Formylamino)-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid
CAS No.	99124-79-5
Molecular Formula	C24H26N4O10
Molecular Weight	530.49 g/mol
Synonyms	3-[[(R)-[4-[(R)-3-Amino-3-carboxypropoxy]phenyl]hydroxyacetyl]amino]-3-(formylamino)-α-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid; (3S,4R)-3-[[(1R)-1-Hydroxy-1-[4-[(1R)-3-amino-3-carboxypropoxy]phenyl]methyl]amino]-3-(formylamino)-4-(4-hydroxyphenyl)-2-azetidinone-1-acetic acid; Azetidinone derivative intermediate; β-lactam intermediate; CAS 99124-79-5
EINECS	Contact for details

Quality Control

Our production of (αr,3S)-3-[[(R)-[4-[(R)-3-Amino-3-Carboxypropoxy]Phenyl]Hydroxyacetyl]Amino]-3-(Formylamino)-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.