Description

5-Bromo-1,3-Difluoro-2-(Phenylmethoxy)-Benzene is a high-value, multi-functional aromatic building block characterized by its bromo, fluoro, and benzyloxy substituents. This compound is essential for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a sophisticated backbone for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as novel liquid crystals or charge-transport molecules, due to its halogenated, electron-deficient aromatic core.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	5-Bromo-1,3-Difluoro-2-(Phenylmethoxy)-Benzene
CAS No.	99045-18-8
Molecular Formula	C13H9BrF2O
Molecular Weight	299.11 g/mol
Synonyms	1-Bromo-3,5-difluoro-2-(benzyloxy)benzene; 2-(Benzyloxy)-1-bromo-3,5-difluorobenzene; Benzene, 5-bromo-1,3-difluoro-2-(phenylmethoxy)-; 5-Bromo-1,3-difluoro-2-(benzyloxy)benzene; 2-Benzyloxy-5-bromo-1,3-difluorobenzene; 99045-18-8; 5-Br-1,3-F2-2-OBn-Benzene
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-1,3-Difluoro-2-(Phenylmethoxy)-Benzene is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with custom purifications available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.