Description

Enkephalin, Ala(2)-Cysteamine(5)- is a synthetic peptide analog of the endogenous opioid peptide enkephalin, modified with alanine at position 2 and cysteamine at position 5. This modification is designed to enhance stability and alter receptor binding affinity, making it a valuable tool for advanced neuroscience and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotech companies investigating pain modulation, neuroprotection, and novel therapeutic pathways for neurological disorders.

Application

• Neuroscience Research: As a key reference standard and active agent in studies of opioid receptor (delta and mu) function and signaling pathways.
• Drug Discovery & Development: Used in high-throughput screening and structure-activity relationship (SAR) studies to design new analgesic and neuroprotective compounds.
• Biochemical Assays: Serves as a substrate or inhibitor in enzymatic assays and receptor binding studies to elucidate mechanisms of peptide metabolism and interaction.
• Academic & Clinical Research: Fundamental tool for investigating the role of enkephalins in pain perception, addiction, mood disorders, and neurodegenerative diseases.
• Peptide Chemistry & Conjugation: The cysteamine moiety provides a reactive thiol group for conjugation with fluorophores, biotin, or other molecules, enabling the creation of labeled probes for imaging and detection.

Basic Information

Product Name	Enkephalin, Ala(2)-Cysteamine(5)-
CAS No.	99043-51-3
Molecular Formula	C27H44N8O7S
Molecular Weight	624.75 g/mol
Synonyms	[Ala2, Cysteamine5]-Enkephalin; H-Tyr-Ala-Gly-Phe-Cysteamine; Ala2,Cysteamine5-Enkephalin; Modified Enkephalin Analog; Opioid Peptide Analog; (5-β-Mercaptoethyl)-[Ala2]-enkephalin; SH-Enkephalin analog
EINECS	Contact for details

Quality Control

Our Enkephalin, Ala(2)-Cysteamine(5)- is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for peptide synthesis and can provide material suitable for use under GLP (Good Laboratory Practice) conditions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.