Description

N(6)-Hydroxymethyladenosine is a modified nucleoside derivative of adenosine, featuring a hydroxymethyl group at the N6 position. This specific modification makes it a valuable intermediate and reference standard in biochemical and pharmaceutical research, particularly in the study of nucleic acid chemistry and epigenetics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for applications in drug discovery, molecular biology, and analytical method development.

Application

• Biochemical Research: Used as a key intermediate in the synthesis of modified nucleotides and oligonucleotides for studying RNA structure and function.
• Pharmaceutical Development: Serves as a building block or reference standard in the discovery and development of nucleoside-based therapeutics, including antiviral and anticancer agents.
• Epigenetics Studies: Acts as a potential analog or tool compound for investigating adenosine methylation pathways and related epigenetic modifications.
• Diagnostic Reagents: Employed in the formulation of specialized reagents and kits for nucleic acid detection and analysis.
• Academic Research: Utilized in university and institutional labs for fundamental research into nucleic acid biochemistry and metabolism.
• Quality Control Standard: Functions as a high-purity analytical standard for HPLC, LC-MS, or NMR to ensure the quality of related pharmaceutical compounds.

Basic Information

Product Name	N(6)-Hydroxymethyladenosine
CAS No.	98897-14-4
Molecular Formula	C11H15N5O5
Molecular Weight	297.27 g/mol
Synonyms	6-(Hydroxymethyl)adenosine; N6-Hydroxymethyladenosine; Adenosine, N6-(hydroxymethyl)-; 98897-14-4; 6-Hydroxymethyladenosine; N6-(Hydroxymethyl)adenosine
EINECS	Contact for details

Quality Control

Our N(6)-Hydroxymethyladenosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.