Description

1H-Imidazol-1-Ylacetonitrile is a versatile and reactive heterocyclic building block, specifically an imidazole derivative functionalized with a cyanoethyl group. This compound is valued for its role as a key synthon in the synthesis of more complex nitrogen-containing molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for constructing novel active compounds and intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing imidazole cores, such as antifungal, antiviral, and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive nitrile and imidazole functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis, including N-heterocyclic carbene (NHC) precursors.
• Material Science Research: Employed in the development of advanced polymers, ionic liquids, and other functional materials that require imidazole-based monomers.
• Bioconjugation and Probe Development: Useful in medicinal chemistry for creating molecular probes and bioconjugates due to its reactive site for further functionalization.

Basic Information

Product Name	1H-Imidazol-1-Ylacetonitrile
CAS No.	98873-55-3
Molecular Formula	C5H5N3
Molecular Weight	107.11 g/mol
Synonyms	1-Cyanoethylimidazole; (Imidazol-1-yl)acetonitrile; 1H-Imidazole-1-acetonitrile; 1-(Cyanomethyl)imidazole; Imidazole-1-ylacetonitrile; 1-Imidazolylacetonitrile; 98873-55-3; Acetonitrile, (1H-imidazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 1H-Imidazol-1-Ylacetonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.