Description

Cefpirome Sulfate is a fourth-generation cephalosporin antibiotic belonging to the β-lactam class, formulated as a sulfate salt for enhanced stability and solubility. This broad-spectrum agent is critical for combating serious bacterial infections, particularly those caused by multi-resistant strains in hospital settings. It is an essential active pharmaceutical ingredient (API) for manufacturers developing sterile injectable formulations for the global pharmaceutical market.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the manufacture of sterile injectable antibiotic formulations.
• Clinical treatment of severe hospital-acquired infections (HAIs) including pneumonia, bacteremia, and sepsis.
• Targeted therapy for infections caused by multi-drug resistant (MDR) Gram-negative bacteria such as Pseudomonas aeruginosa and Enterobacter species.
• Used in veterinary medicine for treating serious bacterial infections in livestock and companion animals.
• Critical component in research and development of new antibiotic combinations and delivery systems.
• Serves as a reference standard in analytical laboratories for quality control and method development.

Basic Information

Product Name	Cefpirome Sulfate
CAS No.	98753-19-6
Molecular Formula	C22H22N6O5S2 • H2SO4
Molecular Weight	612.64 g/mol
Synonyms	Cefpirome Sulphate; HR-810 Sulfate; Cefpiromum Sulfate; CPM Sulfate; (6R,7R)-7-[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetamido]-3-(6,7-dihydro-5H-cyclopenta[b]pyridin-1-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate; Cefpirome Monosulfate; 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5H-cyclopenta[b]pyridinium sulfate
EINECS	Contact for details

Quality Control

Our Cefpirome Sulfate is manufactured under strict quality systems in compliance with cGMP (current Good Manufacturing Practice) guidelines. Each batch undergoes comprehensive analytical testing including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents to meet pharmacopoeial standards (USP/EP). A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and regulatory compliance for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
pH (1% solution)	3.5 - 5.5
Specific Optical Rotation	+70° to +80°
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.