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9-o-Acetyl-Gd3 Ganglioside CAS NO 98743-26-1
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CAS No.:98743-26-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9-o-Acetyl-Gd3 Ganglioside is a specific, acetylated derivative of the GD3 ganglioside, a crucial component of cell membranes with significant roles in cellular recognition and signaling. This modified compound is of high interest in advanced biochemical and pharmaceutical research for studying ganglioside metabolism, cell adhesion, and receptor function. It serves as a critical reference standard and intermediate for researchers and developers in neuroscience, immunology, and oncology, particularly for investigating tumor-associated antigens and developing targeted therapies.
Application
- Biochemical Research Standard: Used as a high-purity reference material for analytical method development and validation in lipidomics and glycomics studies.
- Neuroscience Studies: Critical for investigating the role of gangliosides in neuronal development, synaptic transmission, and neurodegenerative disease models.
- Immunology and Cancer Research: Serves as a target antigen in studies of tumor immunology, antibody production, and the development of cancer vaccines and diagnostics.
- Pharmaceutical Intermediate: Acts as a key synthetic intermediate or precursor in the development of novel glycotherapeutic agents and drug conjugates.
- Cell Biology: Utilized in studies of cell membrane dynamics, lipid raft composition, and signal transduction pathways mediated by glycosphingolipids.
Basic Information
| Item | Details |
|---|---|
| Product Name | 9-o-Acetyl-Gd3 Ganglioside |
| CAS No. | 98743-26-1 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 9-O-Acetyl-GD3; O-Acetylated GD3 Ganglioside; GD3 (9-O-acetyl); 9-O-Acetyl-disialyllactosylceramide; II3(Neu5Ac,Neu5,9Ac2)-GgOse4Cer; Tumor-associated antigen OAcGD3; 9-O-Acetyl-GD3 antigen |
| EINECS | Contact for details |
Quality Control
Our 9-o-Acetyl-Gd3 Ganglioside is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, mass spectrometry (MS), and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Solubility | Soluble in chloroform/methanol/water mixtures |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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