Description

1-(Bromomethyl)-1-Cyanocyclopropane is a versatile and highly functionalized cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive bromomethyl group and a nitrile functionality on the same strained three-membered ring, makes it an invaluable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates containing cyclopropane rings, which are valued for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced activity and selectivity.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials with unique properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing complex chelating ligands and organocatalysts.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Cross-Coupling Reactions: The bromomethyl moiety acts as an excellent electrophile for various palladium-catalyzed cross-coupling reactions to introduce the cyclopropane unit.

Basic Information

Product Name	1-(Bromomethyl)-1-Cyanocyclopropane
CAS No.	98730-78-0
Molecular Formula	C5H6BrN
Molecular Weight	160.01 g/mol
Synonyms	1-Cyano-1-(bromomethyl)cyclopropane; (Bromomethyl)cyclopropanecarbonitrile; 1-Cyanocyclopropanemethyl bromide; Cyclopropanecarbonitrile, 1-(bromomethyl)-; 1-Bromomethyl-1-cyanocyclopropane
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-1-Cyanocyclopropane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.