Description

tert-Butyl 3-Hydroxypropylmethylcarbamate CAS NO 98642-44-5 is a versatile carbamate derivative that serves as a key protected intermediate in advanced organic synthesis. Its value lies in the tert-butyloxycarbonyl (Boc) protecting group, which is crucial for the controlled synthesis of complex molecules, particularly in pharmaceutical development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring amine protection strategies.
• Peptide Synthesis: Used in the preparation of peptide analogs and mimetics where the Boc group protects amino functionalities during coupling reactions.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced crop protection agents and herbicides.
• Polymer Chemistry: Acts as a monomer or chain transfer agent in the synthesis of specialized polyurethanes and other functional polymers.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process R&D for exploring new synthetic pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.

Basic Information

Product Name	tert-Butyl 3-Hydropropylmethylcarbamate
CAS No.	98642-44-5
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	1,1-Dimethylethyl N-(3-hydroxypropyl)-N-methylcarbamate; tert-Butyl N-(3-hydroxypropyl)-N-methylcarbamate; N-(3-Hydroxypropyl)-N-methylcarbamic Acid tert-Butyl Ester; 3-[(tert-Butoxycarbonyl)(methyl)amino]propan-1-ol; Boc-N-methyl-3-aminopropanol; N-Methyl-3-aminopropanol tert-butyl carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Hydroxypropylmethylcarbamate is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest standards of purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, including those for pharmaceutical development (GMP-grade available upon request).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.