Description

Bucolome n-Glucuronide is a key metabolite of the pharmaceutical compound Bucolome, formed via glucuronidation. This compound is of significant importance in pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and the development of analytical reference standards. It is primarily utilized by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in bioanalytical method development and regulatory submission support.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quantification of Bucolome and its metabolites in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Essential for investigating the metabolic pathways, bioavailability, and excretion profiles of Bucolome.
• Bioanalytical Method Development: Used as a standard for developing and validating sensitive HPLC, LC-MS, or LC-MS/MS assays in plasma, urine, or tissue samples.
• Toxicology and Safety Assessment: Employed in studies to understand the safety profile and potential toxicity of Bucolome metabolites.
• Clinical Research: Supports clinical trials by enabling accurate monitoring of drug and metabolite levels in patient samples.
• Impurity Profiling: Acts as a known impurity or degradation product standard for quality control of Bucolome active pharmaceutical ingredient (API).

Basic Information

Product Name	Bucolome n-Glucuronide
CAS No.	98641-06-6
Molecular Formula	C17H19N3O8
Molecular Weight	393.35 g/mol
Synonyms	5-Butyl-1-cyclohexyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 3-Glucuronide; Bucolome Glucuronide; Bucolome 3-O-β-D-Glucuronide; 1-Cyclohexyl-5-propyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 3-Glucuronide (related); Bucolome Metabolite; Bucolome Conjugate
EINECS	Contact for details

Quality Control

Our Bucolome n-Glucuronide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and identity confirmation, suitable for use as a reference standard. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identification (by NMR and/or MS), and other relevant specifications is provided with every shipment to ensure traceability and compliance with research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing at -20°C under inert atmosphere to ensure maximum stability. Keep the container in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR/MS)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.