Description

Raclopride CAS NO 98527-32-3 is a highly selective dopamine D2 receptor antagonist, widely recognized as a critical pharmacological research tool. Its primary value lies in its high affinity and specificity, making it indispensable for neurological and psychiatric research applications. This compound is essential for researchers and pharmaceutical developers in neuroscience, particularly for studying dopamine pathways, receptor binding assays, and the development of treatments for disorders like schizophrenia and Parkinson's disease.

Application

• Neuroscience Research: A standard radioligand for in vitro and in vivo binding studies to characterize dopamine D2 receptors.
• PET Imaging Tracer: Used in Positron Emission Tomography (PET) scans, often as [11C]Raclopride, to visualize and quantify D2/D3 receptor availability in the living brain.
• Pharmacological Profiling: Employed in high-throughput screening (HTS) to evaluate the potency and selectivity of novel compounds targeting dopaminergic systems.
• Behavioral Studies: Utilized in animal models to investigate the role of dopamine in locomotion, reward, and cognition.
• Drug Development: Serves as a reference standard in the preclinical development of antipsychotic and neurologic medications.
• Academic & Clinical Research: Fundamental tool for universities and research hospitals studying the neurochemical basis of mental health and neurodegenerative diseases.

Basic Information

Product Name	Raclopride
CAS No.	98527-32-3
Molecular Formula	C15H21ClN2O3
Molecular Weight	312.79 g/mol
Synonyms	(S)-(-)-Raclopride; FLA 870; Raclopride tartrate; (S)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide; (S)-(-)-3,5-Dichloro-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-hydroxy-6-methoxybenzamide; (S)-3,5-Dichloro-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide; FLA-870
EINECS	Contact for details

Quality Control

Our Raclopride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and residual solvent testing. A detailed Certificate of Analysis (COA) providing full specification data is supplied with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-enantiomer)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.