Description

n-(4-Bromo-2-Thienyl)Acetamide is a specialized brominated thiophene derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive halogen site and a protected amine functionality, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Chemical Synthesis: Versatile intermediate for Suzuki-Miyaura and other cross-coupling reactions, as well as nucleophilic substitution, to create diverse heterocyclic libraries.
• Ligand and Catalyst Development: Used to prepare novel ligands for transition metal catalysis and organocatalysts.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	n-(4-Bromo-2-Thienyl)Acetamide
CAS No.	98453-24-8
Molecular Formula	C6H6BrNOS
Molecular Weight	220.09 g/mol
Synonyms	N-Acetyl-4-bromo-2-aminothiophene; 4-Bromo-2-acetamidothiophene; 2-Acetamido-4-bromothiophene; Acetamide, N-(4-bromo-2-thienyl)-; 4-Bromothiophene-2-acetamide; (4-Bromo-2-thienyl)acetamide; 98453-24-8; 4-Bromo-2-thiopheneacetamide
EINECS	Contact for details

Quality Control

Our n-(4-Bromo-2-Thienyl)Acetamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.