Description

5-Chloro-3-Fluoro-2-Methoxynitrobenzene, also known as 4-Chloro-2-Fluoro-5-Nitroanisole, is a high-purity, multi-functional aromatic intermediate of significant commercial importance. Its unique halogenated and nitrated anisole structure makes it a versatile building block for synthesizing complex molecules, particularly in advanced pharmaceutical and agrochemical research. This compound is essential for manufacturers and R&D laboratories seeking a reliable, high-quality precursor for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing halogenated aniline or benzamide motifs.
• Agrochemical Synthesis: Serves as a crucial precursor for developing novel herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes and organic pigments where its substitution pattern imparts specific color and stability properties.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, including liquid crystal displays and organic light-emitting diodes.
• Organic Synthesis & Research: A valuable reagent in academic and industrial research laboratories for constructing complex heterocyclic compounds and exploring new chemical reactions.
• Polymer Additives: Can be utilized in the synthesis of specialized monomers or polymer additives to modify material properties.

Basic Information

Product Name	5-Chloro-3-Fluoro-2-Methoxynitrobenzene
CAS No.	98404-03-6
Molecular Formula	C7H5ClFNO3
Molecular Weight	205.57 g/mol
Synonyms	4-Chloro-2-Fluoro-5-Nitroanisole; 1-Chloro-3-Fluoro-2-Methoxy-5-Nitrobenzene; 2-Methoxy-5-Nitro-1-Chloro-3-Fluorobenzene; 5-Nitro-2-Chloro-4-Fluoroanisole; 98404-03-6; 4-Chloro-2-fluoro-5-nitro-1-methoxybenzene; 2-Chloro-4-fluoro-5-nitroanisole
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoro-2-Methoxynitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.