Description

Boc-Dl-4-tert-Butyl-Phe CAS NO 98375-50-9 is a protected amino acid derivative, specifically the tert-butoxycarbonyl (Boc) derivative of 4-tert-butyl-DL-phenylalanine. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, where the Boc group provides orthogonal protection for the amine functionality. It is essential for researchers and manufacturers in pharmaceutical R&D and fine chemical synthesis who require high-purity, specialty intermediates to develop novel peptide-based therapeutics and bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key protected amino acid for the controlled assembly of complex peptide sequences in research and development.
• Pharmaceutical Research: Used in the discovery and synthesis of novel peptide drugs, hormones, and enzyme inhibitors.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or peptide-based molecular probes for diagnostic applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new biologically active molecules.
• Academic & Institutional Research: Fundamental building block in university and institutional labs for studying protein structure-function relationships and peptide science.
• Fine Chemical Production: Intermediate in the multi-step synthesis of more complex, non-peptidic organic molecules requiring the 4-tert-butyl-phenylalanine moiety.

Basic Information

Product Name	Boc-Dl-4-tert-Butyl-Phe
CAS No.	98375-50-9
Molecular Formula	C₁₈H₂₇NO₄
Molecular Weight	321.41 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-4-tert-butyl-DL-phenylalanine; Boc-4-tert-butyl-DL-phenylalanine; DL-4-tert-Butylphenylalanine N-Boc derivative; N-Boc-4-tert-butyl-DL-phenylalanine; tert-Butyl N-[(RS)-2-amino-3-(4-tert-butylphenyl)propanoyl]carbamate; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(4-tert-butylphenyl)propanoic acid; Boc-DL-4-tBu-Phe-OH
EINECS	Contact for details

Quality Control

Our Boc-Dl-4-tert-Butyl-Phe is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with the standards expected in fine chemical and pharmaceutical intermediate supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.