Description

Benzonitrile, 4-[1-Methyl-4-(Trifluoromethyl)-1H-Imidazol-2-Yl]- is a high-value, heterocyclic aromatic nitrile building block featuring a trifluoromethylated imidazole moiety. This compound is critical for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by pharmaceutical and agrochemical R&D sectors for the development of novel active ingredients, where its unique structure can impart enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group contributes to improved lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tags to study enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up campaigns for client-specific molecules.

Basic Information

Product Name	Benzonitrile, 4-[1-Methyl-4-(Trifluoromethyl)-1H-Imidazol-2-Yl]-
CAS No.	98298-45-4
Molecular Formula	C12H8F3N3
Molecular Weight	251.21 g/mol
Synonyms	4-(1-Methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)benzonitrile; 2-(4-Cyanophenyl)-1-methyl-4-(trifluoromethyl)imidazole; 1-Methyl-2-(4-cyanophenyl)-4-(trifluoromethyl)-1H-imidazole; 4-(1-Methyl-4-trifluoromethylimidazol-2-yl)benzonitrile; 98298-45-4; 4-[1-Methyl-4-(trifluoromethyl)imidazol-2-yl]benzonitrile
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-[1-Methyl-4-(Trifluoromethyl)-1H-Imidazol-2-Yl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to cGMP and ISO 9001 standards ensures reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.