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n-Sulfooxy-2-Aminofluorene CAS NO 98253-52-2
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CAS No.:98253-52-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Sulfooxy-2-Aminofluorene is a crucial sulfated metabolite and a key intermediate in the study of carcinogenic aromatic amines. This compound is of significant importance for researchers and manufacturers in the fields of toxicology, pharmacology, and analytical chemistry, particularly for investigating metabolic activation pathways and DNA adduct formation. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on chemical carcinogenesis and drug safety assessment.
Application
- Biochemical Research: Used as a reference standard and intermediate in studies of metabolic activation of 2-aminofluorene and related aromatic amines.
- Toxicology Studies: Essential for investigating the mechanisms of chemical carcinogenesis, specifically the formation of DNA adducts.
- Analytical Chemistry: Serves as a high-purity analytical standard for method development and validation in HPLC, LC-MS, and other chromatographic techniques.
- Pharmacology: Employed in research on drug metabolism and the safety profiling of new chemical entities to understand potential genotoxic metabolites.
- Academic Research: A vital tool for universities and research institutes conducting fundamental studies in chemical biology and environmental toxicology.
Basic Information
| Product Name | n-Sulfooxy-2-Aminofluorene |
| CAS No. | 98253-52-2 |
| Molecular Formula | C₁₃H₁₁NO₄S |
| Molecular Weight | 277.30 g/mol |
| Synonyms | 2-Aminofluorene N-sulfate; 2-AF N-sulfate; N-Sulfonatooxy-2-aminofluorene; 2-Aminofluorenyl sulfate; 9H-Fluoren-2-amine, N-sulfooxy-; AAF N-sulfate (related); Sulfoconjugate of 2-aminofluorene |
| EINECS | Contact for details |
Quality Control
Our n-Sulfooxy-2-Aminofluorene is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is characterized and tested using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (MS) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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