Description

1,2-Ethanediol-1-14C, 2,2-Diphenyl-1-o-Tolyl- is a specialized isotopically labeled compound, where a carbon-14 atom is incorporated at a specific position within the ethanediol backbone, attached to a complex diphenyl-tolyl moiety. This product is critical for advanced research and development, enabling precise metabolic and pharmacokinetic studies through radiotracer techniques. It is primarily required by pharmaceutical R&D laboratories, agrochemical research facilities, and academic institutions focused on organic synthesis and reaction mechanism elucidation.

Application

• Radiotracer Synthesis: Serves as a key labeled precursor for creating carbon-14 tagged molecules in drug discovery and development.
• Metabolic Pathway Studies: Used to trace the absorption, distribution, metabolism, and excretion (ADME) of novel chemical entities in biological systems.
• Pharmaceutical Research: Essential for investigating the fate and degradation pathways of active pharmaceutical ingredients (APIs) and their metabolites.
• Agrochemical Development: Applied in environmental fate studies to understand the breakdown and movement of pesticides and herbicides.
• Organic Synthesis Research: Acts as a building block for synthesizing complex, isotopically labeled compounds for mechanistic studies.
• Regulatory Submission Support: Provides the necessary data for regulatory filings that require radiolabeled studies.

Basic Information

Product Name	1,2-Ethanediol-1-14C, 2,2-Diphenyl-1-o-Tolyl-
CAS No.	112745-52-5
Molecular Formula	C21H20O2 (with 14C at position 1)
Molecular Weight	~304.39 g/mol (exact mass varies with 14C content)
Synonyms	1,2-Ethanediol-1-14C, 2,2-diphenyl-1-(2-methylphenyl)-; [1-14C]Ethylene glycol, 2,2-diphenyl-1-o-tolyl-; 2,2-Diphenyl-1-o-tolylethane-1,2-diol-1-14C; Carbon-14 Labeled 1,2-Diphenyl-2-(o-tolyl)ethane-1,2-diol; Radiolabeled o-Tolyl Diphenyl Ethanediol; 14C-Labeled Atrolactic Acid Derivative Precursor
EINECS	Contact for details

Quality Control

Every batch of this isotopically labeled compound is produced and tested under stringent conditions to ensure radiochemical purity, chemical purity, and specific activity meet exacting research standards. Our quality system includes verification via HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the analytical results, specific activity (mCi/mmol or GBq/mmol), and expiration date.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label and Certificate of Analysis. Due to the presence of the carbon-14 isotope, all handling and storage must comply with local and international regulations for radioactive materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97.0%
Specific Activity	50-60 mCi/mmol (Custom ranges available)
Solubility	Soluble in common organic solvents (e.g., DMSO, Acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.